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  • Hacker News
  • I wonder if this could help explain why creatine helps mitigate the effects of sleep deprivation. Since creatine aids in water retention.

    https://pubmed.ncbi.nlm.nih.gov/16416332/

  • It’s not clear how water retention would help with the needed flushing.
  • Mix your cheap instant coffee with creatine powder and ORS for that ultimate early morning flavor bomb!
  • I would imagine it has more to do with its principal function in recycling ADP back to ATP (fuel for cells). People who are sleep deprived also have impaired glucose metabolism, meaning that the cellular "fuel pipeline" is impeded. Perhaps creatine is especially helpful under these conditions.

    https://pmc.ncbi.nlm.nih.gov/articles/PMC1991337/

  • I slept around 5 hours last night split up into two periods because my baby daughter woke up crying from fever and wanted to play / was hallucinating / etc. She's totally fine now but I am wondering if there is a correlation between dementia and having kids.
  • What have you done when your toddler wakes up at random hours during the night to interrupt your sleep and come and play? That's what has truly obliterated our sleep. Everything else was a passing fad that was minimally painful at best..
  • Ah, those days were the absolute grinder for me. How a precious and sweet little baby girl can become an absolute monster all night long, and then wake up the next day back to her normal self while leaving me a hollowed out mess of a human is a mystery for science to solve someday.
  • I mean the baby stage doesn't last very long. I dont even remember the sleepless nights from my own kids anymore lol

    Chronic sleep deprivation is the larger issue. And how we really don't have treatments on how to fix that, and how ultimately sleep phase issues are a social issues (being forced to follow a fixed modern schedule). Not to mention how closely that's tied to ND people. So a lot of us deal with sleep issues since we were little, but work and school dont give us the flexibility we need. For example, flex hours could be helpful here. I would rather work 10am to 6pm or 11am to 7pm most days. Or 5-6 hours during the day and 2-3 hours late at night.

  • This kind of fear is a quick route to insomnia. One of the most effective ways to reduce sleep is to worry about it.
  • I’m on my 3rd (she’s 1 week old today) at 42. With the first 2 it was only terrible for the first couple months. Once I just got used to going to sleep at 9:30 I was mostly fine.
  • Memory loss from sleep deprivation is an evolutionary advantage. If you remembered how rough the first few months of new children are, you wouldn't do it again.
  • I remember this quote from when we had young kids:

    "Insanity is hereditary. You can get it from your children."

    And then as soon as they are in their 20s and reasonably self sufficient we had to get a puppy to keep me sane!

  • Probably negatively correlated cause you have someone to interact with in your old age/better chance of community :)
  • Could ADHD be caused by a broken flushing response? Lots of flushing followed by intense focus caused by the tabula rasa?
  • Even if this is a possible factor it most certainly would not be the only cause.
  • Not sure if it's related, but I have way more ADHD-like symptoms if I'm on late sleep schedule, but sleeping the same amount of hours.
    by Geee
  • I'm not an expert, but that wouldn't really fit with my understanding of ADHD. It's not that we have a lack of attention ("defecit" of attention, as the name suggests), it's an impaired ability to direct it.

    To abuse a metaphor, the sleep-deprivation-induced spontaneous CSF flush is slamming on the brakes of a car, and ADHD related attention shifts would be more like a drunk toddler is turning the steering wheel wherever they please, but the gas/brakes still work fine.

  • I suppose it's possible, but it seems less likely to me because ADHD is a life long neurodevelopmental disorder that shows [visible physical changes in the brain on scans](https://pmc.ncbi.nlm.nih.gov/articles/PMC7879851/). That said, there are statistically more people with narcolepsy who have ADHD, and the same goes for sleep apnea. There's a number of hypotheses I've read as to why, to name a couple: related epigenetic causes, or [possible misdiagnosis](https://pmc.ncbi.nlm.nih.gov/articles/PMC7336577/) (narcolepsy is much harder to diagnose than ADHD if you don't have textbook symptoms). So there is definitely something there.
  • Disordered sleep can cause executive dysfunction similar to ADHD, but it does not cause ADHD. It certainly can exacerbate it or be diagnosed incorrectly.
  • Rest in peace to all the college dudes covering the whole syllabus within 24 hours of the exam
  • Not a college dude, but i used to work on shits (including night shifts) and adjusting to and from a five-nights (23:30-07:30) shift isn’t that pleasant either.
    by znpy
  • It is always great to follow the instructions from a psychiatrist [1].

    [1] https://thelastpsychiatrist.com/2007/08/how_to_take_ritalin_...

    by wslh
  • I wonder if a 30-min nap improves the situation. But I need to tell the brain to hold the flushing until the nap.
  • > I wonder if a 30-min nap improves the situation.

    I pretty much wait until I feel drowsy, and then take a 15-30 minute nap

  • There's controversy over exact mechanisms involved in glymphatic function, so suffice it to say that allegedly even just NSDR / yoga nidra will engage a rest deep enough for glymphatic function to engage/improve
  • Anecdotally, it seems to. I have laid down and closed my eyes even for a short while. And believe that I have even had a "flushing" sensation, that feels like a mental fog being lifted (or "drained", I guess).

    I pop up 5 minutes later and feel completely refreshed.

  • What I’m picking up here is that if I can just get an automated CSF circulator installed I won’t need to sleep or get distracted when I’m tired. That was the point of this article, right?
  • So... can we trigger it manually? I'd love to be able to lay down and press the 'flush brain' button.
  • Searching back, as I recall a video that was supposed to cause [increased] CSF flow, I did find this - https://news.ycombinator.com/item?id=34764730 about suggestions some learning difficulties might be due to interrupted CSF fluid flow.

    The video (?) was related to clearing of plaques from the brain with a view to mitigating Alzheimer's effects.

    It was not the NSDR (Non-Sleep Deep Rest) videos a sibling commenter posted.

  • Research on NDSR, I have been using this for days I had to wake up without proper rest.

    If you have 15m, search this on YT for a guided practice and test it yourself.