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- Hacker News
- Microplastics are a huge issue-- reducing your exposure is of the utmost importance imo. I go to a longevity clinic that tests, and was recommended this product MicroCleanse by Hazel's. Have seen a material reduction in level 2 build up.by hps79
- > Maintaining optimal midlife vascular health was associated with up to 12.6 additional dementia-free survival years,
Stay on top of your cardiovascular health. Even moderate diet and lifestyle changes can have a significant impact on the last decade of your life. These things compound over decades.
by Aurornis - Being human, I think more about the number of dementia years than number of dementia-free years. Could having good dietary, sleep, and exercise habits result in living longer with dementia?
I've hard about cognitive reserve and how healthy lifestyle choices can build that. But I never read about ways to minimize the number of years you have to live with dementia. I wish I could sign an order that would grant me a dignified death once I'm deemed no longer fit to make that decision.
by criddell - I have always had a very low blood pressure, below what's considered "normal." I never feel dizzy when standing up, though. Is this still a risk factor for dementia?by John7878781
- This is a question for your doctor.by organsnyder
- The work of Dr. Rick Johnson is perhaps relevant. He links the effects of fructose on the mitochondria, which then affects the neurons in the brain, over time.
This hypothesis makes much more sense to me when you think to the associated diseases (diabetes, heart disease etc...)
You can get a overview of his research on this podcast (approx 75min): https://www.youtube.com/watch?v=59Oje6n2JLU
by ajx1001 - In the context of TFA, what hypothesis makes much more sense to you than what alternative?by n8henrie
- If anyone wants to go down a rabbit hole, go search for topics around fructose corn syrup, visceral fat and artery plaque. It can play a substantial role in vascular health. I'm not a doctor but there's a bunch of studies posted online about this and my doctor also agreed when I asked him about it.
Avoiding fructose corn syrup is a really good idea. It's in a ton of sugary drinks. It really messes with inflammation in your body and your liver materializes it in a very similar way as alcohol. Basically both are bad and can cause similar issues.
For me personally I walk a few miles a day for 15+ years and I'm in ok shape. Cutting out Arizona iced tea (has a lot of fructose corn syrup) has made a material difference in how my body operates, I used to drink 1-2 cans a day for a while. Nowadays going 18 hours without food is no problem, I don't have mid-day tired spikes and I didn't change what I eat. I can't explain it but it feels like it reset something.
When I've been on vacation in other countries outside of the US for a few weeks, I noticed the same thing (less hungry, more energy, etc.) and a commonality there is I also didn't drink large amounts of fructose corn syrup. There's a lot of variables I'm sure but I can say I feel a difference for the better after stopping and I've now repeated these feelings when doing normal things locally.
by nickjj - > Hypertension was defined as a systolic blood pressure of 140 mm Hg or higher, a diastolic blood pressure of 90 mm Hg or higher, or the utilization of blood pressure-lowering medications.
Whoever defined this, thank you for having common sense!
This stood out to me because there are so many lunatics defining it as 121/80 or even 121/70 with the backwards idea that the systolic is more important. Worse still is when they insist that something as low as 100/65 is optimal despite complaints of dizziness. All the while hammering home that you should chug a million gallons of water and deprive yourself of sodium. It's like they're trying to make people miserable.
by sublinear - Blood pressure varies significantly throughout the day and is often measured incorrectly at doctors offices. It's a good idea to get a home cuff BP machine and keep track of it yourself after reading up on how to use the machine. Otherwise you might get recommended medicine incorrectly, or you could get a false sense of security.by bufordtwain
- The 120/80 benchmark isn't lunacy. Most people in the west have issues with hypertension because that's the direction it goes due to the common risk factors.
If you're at 135/85, and you're middle aged / younger, and your diet and lifestyle aren't already optimized, it's something you should probably care about, not look for the next highest rung on the ladder so that you can celebrate for being below it.
by hombre_fatal - The blood pressure-lowering medications was a kick in the crotch. I've had primary hypertension (i.e., doctors have no explanation for why) since I was a teenager playing fifteen hours of tennis a week with a low body fat percentage and healthy eating habits.
Nothing I've ever tried has fixed this, including scratch-cooking everything for months, no meat, no salt, for months. Distance running. Weightlifting. Lots of sleep. I literally don't even have to work the rest of my life and am in my 40s, so no stress, either. I guess I'm just screwed!
by KPGv2 - The importance of walking can not be overstated. Walking for 30 mins every other day will dramatically improve your life if you are sedentary. If you can't do 30 minutes, start with 15.by johsole
- Had an uncle who swore by this. He died at 57 of ALS.
That obviously doesn't mean walking is bad, I just mean to point out that even those people who believe in it as a silver bullet, can be hit with something totally out of left field.
Life is really quite brutish and short. You can do all the right things, and die early. All the wrong things, and live a long time. Take care of yourself for sure, but also find a balance and enjoy your life.
by jr3592 - Walking is great, and you should do it for reasons other than cardio/circulation health too (walk in nature, rest for eyes, ankle strength, socialising, touch-grass moment etc).
But if you're doing it primarily for health, there's one other thing I'd suggest.
High rep bodyweight squats and lunges.
If you build up to it very gradually there's no risk of hurting your knees. It's the best example of "motion is lotion". After a few months of daily squats, climbing stairs will feel effortless. I'm 40 and I can tell you you'll notice the difference.
A 100 squats at relaxed pace takes about 5 minutes for me. 10 mins for 150. 100 walking lunges in 10 mins. There's no hurry/competition. You can take your time to catch your breath. I've done 250 or so in 30 mins once every 2 or 3 weeks. But I feel that's not conducive to daily work. I get tired.
Once you get acquainted to this to the point where a 100 reps of squats/lunges don't make you sore the next day, or hurt the joints, then the heart rate you achieve from this will be similar to a relaxed zone 2 run.
And the health benefits are similar to walking. improved blood sugar and blood pressure.
My goal is to be able to do this for 20 to 30 mins twice or thrice a week. That might be some 300 to 400 squats.
I've been doing his way of training for a few years now, and I love it because this is what has be train consistently. not going to gym or tracks, or playing sports.
I like this, and recommend this over walking to anyone who can't seem to get the time to walk because it takes less time to get similar health benefit, doesn't need space/dressing-up/socialising/commute.
If you want info on this, kboges on youtube is the man. here are his amazing squat/legs related videos:
- https://www.youtube.com/watch?v=guG1LT7ejDU - he does 525 reps in one set. says it took him 20 mins
- https://www.youtube.com/watch?v=zWXToSCaq-Q - he does 100 constant tension squats in 2 mins
- https://www.youtube.com/watch?v=0euDDJu6GnQ - deep knee bends, aka hindu squats
- https://www.youtube.com/watch?v=TqNP_PiEalg - his take on squats busting your knees
ofc, not a doctor, dyor, listen for sharp pains etc and progress very slowly if you don't want to get hurt! you have your whole life to improve, so there's no hurry.
by npras1 - Lifting weights also helps.
I'd argue that if someone wants to go beyond walking into running or even jogging, they ought to get their strength up so they don't have blood sugar crashes or cramps. It's never a bad idea to gain some muscle.
by sublinear - For those who are inclined, I recommend running instead (even if you think you aren't a runner)
My body has been completely transformed from 15 years of running. I'm 5'7" and 135 pounds at age 41. My face looks thin, I have a better body than most 20 year olds. I gave myself the best gift that I could possibly give myself.
If they could distill 15 years of running (5x per week) and put it in pill form, I truly believe it would be the most valuable thing medicine has ever created.
All it takes is 45 minutes per day for 5 days per week. And you can actually have fun while doing it! It takes a long time to get to that point but it's so worth it.
by scottious - You are going to die, and it's a painful ugly business.
The right to die humanely is the single most under-regarded and under-valued aspect of life hygiene.
by _wire_ - Fortunately some jurisdictions are death wise enough to provide humane means that we can request from a health practitioner.by tejohnso
- Previous studies have shown that heart health at 50 predicts brain health at 75.
This study is interesting in that it quantifies the benefit as 12.5 extra dementia-free years. People with 0 risk factors had 30 years of dementia-free survival, vs 17.5 years for people with all 3 risk factors measured.
The risk factors in this specific study are blood pressure, diabetes (HbA1c), and smoking. You could reasonably also include cholesterol/ApoB, inflammation (hs-CRP), and perhaps Lp(a) as potential risk factors.
by brandonb - It's mostly luck and genetics, but good sleep matters.
My mother died from Alzheimer's at 77 but wrote down her symptoms as early as 60, a full six years before her diagnosis.
Prior to her diagnosis, she walked her dog two miles a day, had an ideal weight, ate organic, never drank or smoke, used her brain constantly, and enjoyed a happy social life.
The only problem I saw with her was she was a very light sleeper.
Her aunt also died from Alzheimer's and was super healthy when diagnosed too.
Meanwhile the 103-year-old lady at my mother's former care facility is still sharp as a tack and reads daily without needing glasses.
by sys32768 - Are you aware of her APOE3/APOE4 status?
- Yes. The time to fix your health is now. Any unhealthy habits put time on the biological clock, and they'll just get harder to undo later. This is true if you're 20, 40, or 60. Plaque even starts building up on the arteries of healthy teenagers. It all adds up.
But don't read this and panic or beat yourself up, that's a waste of energy. That's choosing the punishment instead of the fix.
Instead, quietly start doing one small healthy habit. If you stop, don't revert to self-punishment again. Just quietly get back to it. Stubbornly persist until you've won.
by asdfman123 - yep.
eat healthy food as much as possible.
walk. exercise. and SLEEP.
by throwawalien - I just watched this video by a doctor, and his point was every one of his ER patients had a problem that was years in the making (except for 1, a little girl who swallowed a battery)
I Saw 120 Patients This Week. Here's Why They Were Actually Sick. https://www.youtube.com/watch?v=UiVKh97rJsg