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  • Then my brain must be full of scars.
  • In mice.
  • I remember having it drilled into me in High School that unless you did well on your finals:

    1. You wouldn’t get the score you needed to get into a good University and/or accepted into the course you wanted. 2. If you didn’t get into that course, you wouldn’t be able to do <x> for a career. 3. If you DID get into the course you wanted, it needed to be at a top University (which of course required an even higher entry score) or else you’d find it hard to get a job afterwards.

    Imagine all of that stress: Telling 16-18 year olds that unless you ace your tests, you won’t be able to do what you want to in life.

  • For research in human spheres: https://birthpsychology.com/ - really interesting material!
  • Not a scar IMHO, but a wound that can be healed. SETD7 is a Histone Methyltransferase. Meaning it attaches methyl groups to DNA which turns genes off. But there are enzymes that remove these methyl groups as well and they are called Demethylases [1]. Many of these enzymes can be stimulated by their nutritional cofactors which are things like Zinc, Iron, and Riboflavin.

    I am a product of early life trauma. Knowing these thing have helped me tremendously.

    [1] https://www.uniprot.org/uniprotkb/Q8NB78/entry

  • Whenever I’m having a dream at night, it’s always about my childhood and always at the place I grew up. It feels like my mind is a prisoner of the place I grew up. Childhood stress and trauma is deeply burnt into my brain I guess
  • Not to play down anyone's stressful life experiences, but the sort of stress they're talking about in this article is more typically correlated with stressors like violence, hunger, or institutionalization in the first decade of life.

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Early-life stress leaves a 'scar' inside brain cells in mice · Birbla