CRISPR tech selectively shreds cancer cells, including "undruggable" cancers
1002 pts, 220 comments
1002 points · 220 comments · Add your take →
Top Hacker News Stories – June 12, 2026 (Summarized)
Recent top stories on Hacker News include a breakthrough in CRISPR technology that selectively destroys cancer cells, including previously "undruggable" types, garnering over 1,000 points and 220 comments. Another notable post discusses the development of electric motors that eliminate the need for rare earth metals, attracting 717 points. Additionally, a detailed guide on setting up a local coding agent on macOS received significant attention with over 500 points, reflecting ongoing interest in practical developer tools.
Nobody ever gets credit for fixing problems that never happened (2001) [pdf]
793 pts, 263 comments
793 points · 263 comments · Add your take →
Electric motors with no rare earths
717 pts, 218 comments
717 points · 218 comments · Add your take →
How to setup a local coding agent on macOS
507 pts, 127 comments
507 points · 127 comments · Add your take →
Putt.day a daily mini golf game
317 pts, 112 comments
317 points · 112 comments · Add your take →
Write for One Person
285 pts, 81 comments
285 points · 81 comments · Add your take →
A dumpster arrived behind my university's library
189 pts, 178 comments
189 points · 178 comments · Add your take →
Ported my C game to WASM, here's every bug that I hit
116 pts, 111 comments
116 points · 111 comments · Add your take →
Factoring "short-sleeve" RSA keys with polynomials
96 pts, 4 comments
96 points · 4 comments · Add your take →
Python 3.14 garbage collection rigamarole
94 pts, 76 comments
94 points · 76 comments · Add your take →
Exploring building a tiny FUSE filesystem
79 pts, 15 comments
79 points · 15 comments · Add your take →
StackScope – I crawled over 40k indie launches to see what they ship
67 pts, 21 comments
67 points · 21 comments · Add your take →
Being an old school web-based sports sim dev in the era of vibe coded games
66 pts, 57 comments
66 points · 57 comments · Add your take →
Asciline – real-time ASCII video rendering engine
65 pts, 25 comments
65 points · 25 comments · Add your take →
Script to bulk delete Claude chats from the web UI
60 pts, 21 comments
60 points · 21 comments · Add your take →
Launch HN: BitBoard (YC P25) – Analytics Workspace for Agents
58 points · 25 comments · Add your take →
Chili peppers of the world: cultivars, species, and heat
50 points · 10 comments · Add your take →
4× RTX Pro 6000 Blackwell on Water, and the One Card That Wouldn't Behave
45 points · 53 comments · Add your take →
A calculator that doesn't round
29 points · 24 comments · Add your take →
Cooling at the Speed of Light
28 points · 2 comments · Add your take →
Infineon to open fab in Germany as part of sovereignty push
23 points · 13 comments · Add your take →
Honeypot Design
22 points · 4 comments · Add your take →
The ghost domain problem in DNS, and what we're doing about it
18 points · 8 comments · Add your take →
SharkClean MCP
15 points · 4 comments · Add your take →
Ttar 2.4 KB freestanding TAR archiver written in C, no Libc
9 points · 0 comments · Add your take →
Building a plugin system without runtime, storage, or shared JavaScript context
9 points · 1 comments · Add your take →
Squishy & Friends – Claude Fabel 5 coded a game and it is good
5 points · 3 comments · Add your take →
MicroECS – entity component system library in Python/NumPy
5 points · 0 comments · Add your take →
Get weekly best stories
One email with the best technology stories and topic pages. No spam.